Crohn's disease is a chronic inflammatory bowel disease (IBD) that can affect any part of the digestive tract. Symptoms include severe abdominal pain, persistent diarrhea, fatigue, weight loss, and rectal bleeding. It is now understood to involve a dysregulated immune response to gut bacteria in genetically susceptible individuals. Microbiome research has identified specific bacterial imbalances in patients making gut health a central focus of emerging treatment strategies.